FIG. 1.

Cross-clade anti-HIV-1 T-cell responses to clade A, B, and C 15-mer peptide pools. Cross-clade T-cell reactivity was assessed using (A) clade B Gag, Nef, Pol-1, Pol-2, Rev, and Tat and (B) clade A and C Gag and Nef. Responses are shown as the number of IFN-γ-expressing cells per million PBMCs. Serum-derived Gag, Nef, and Pol sequences were subtyped and are indicated by different symbols. For two patients, no subtyping data were available (NA). The median responses are indicated for each group by a horizontal line. Cross-clade B Gag and Nef responses are replotted in panel B.