FIG. 6.
Viremia and clearance of the MVMp and WT-VP3B viruses in SCID mice. Genomic copy numbers of the MVMp and WT-VP3B viruses in blood cells obtained from two oronasally inoculated SCID mice (108 PFU/mouse) at the indicated dpi. Low-molecular-weight DNA isolated from an equivalent of 1 μl of blood cells was subjected to semiquantitative PCR amplification of a 1.25-kbp region of MVM genome and loaded in 1% agarose gel. PCR amplification of measured numbers of viral particles (determined by hemagglutination) from the purified viral stocks used to inoculate the mice is shown in the left lanes.