FIG. 4.

Expression of CD25 on T cells in HIV-1-infected human lymphoid tissue ex vivo; comparison of the distributions of CD25 among different cell populations in uninfected and ex vivo-infected lymphoid tissue after 12 days in culture. The data were obtained in experiments using 54 pooled tissue blocks per condition from a single donor. (A) Distributions of CD25 among CD8⁻ CD3⁺ lymphocytes (left) and among CCR5⁺ CD8⁻ CD3⁺ lymphocytes (right) in uninfected tissue. The contour plots are at log 50% probability. Presented is one representative experiment out of six. (B) The distributions of CD25 among CD8⁻ CD3⁺ lymphocytes (left) and among p24⁺ CD8⁻ CD3⁺ lymphocytes in tissue infected with isolates 314 and 4223 from patient 1047; one representative experiment out of six matching that presented in panel A is shown.