Table 1.
Claudin-4 immunoexpression depending on investigated parameters
|
Parameter/ p value |
Claudin-4 (FSS) |
|
|
Age (years) |
<50 |
7.5 |
|
50-59 |
5.8 |
|
|
60-69 |
6.0 |
|
|
70-79 |
4.7 |
|
|
p value (χ2 test) |
0.509 |
|
|
Gender |
M |
5.4 |
|
F |
5.7 |
|
|
p value (Fisher’s test) |
0.741 |
|
|
Smoking status |
Smoker |
5.6 |
|
Non-smoker |
4.0 |
|
|
p value (Fisher’s test) |
0.383 |
|
|
Tumor type |
Squamous cell carcinoma |
6.1 |
|
Adenocarcinoma |
4.9 |
|
|
Large cell carcinoma |
5.6 |
|
|
p value (χ2 test) |
0.211 |
|
|
Tumor subtype |
Acinar |
2.2 |
|
Papillary |
2.2 |
|
|
Lepidic |
6.0 |
|
|
Mucinous |
6.5 |
|
|
Cribriform |
7.5 |
|
|
Micropapillary |
7.0 |
|
|
Solid |
7.7 |
|
|
Basaloid squamous cell carcinoma |
6.4 |
|
|
Non-keratinizing squamous cell carcinoma |
6.1 |
|
|
Large cell carcinoma |
5.6 |
|
|
p value (χ2 test) |
0.002 |
|
|
Tumor grade |
G1 (well differentiated) |
6.0 |
|
G2 (moderate differentiated) |
4.4 |
|
|
G3 (poorly differentiated) |
6.3 |
|
|
p value (χ2 test) |
0.011 |
|
|
Vascular invasion |
Absent |
4.5 |
|
Present |
7.0 |
|
|
p value (Fisher’s test) |
<0.001 |
|
|
Tumor stage |
I |
3.6 |
|
II |
3.9 |
|
|
III |
6.6 |
|
|
IV |
6.8 |
|
|
p value (χ2 test) |
0.001 |
|