Table 3.
Multivariable analyses of nutritional scores to predict 1-year poor neurological functional outcome.
| Nutritional status | Events, N (%) | Unadjusted | Model 1 | Model 2 | Model 3 | ||||
|---|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | ||
| BMI | |||||||||
| Continuous | ... | 0.98(0.92–1.06) | 0.661 | 0.98(0.91–1.06) | 0.655 | 1.02(0.93–1.11) | 0.731 | 1.02(0.93–1.11) | 0.736 |
| Normal | 14(26.40) | Reference | Reference | Reference | Reference | ||||
| Underweight | 85(29.00) | 0.88(0.45–1.70) | 0.701 | 0.91(0.46–1.80) | 0.911 | 0.71(0.33–1.55) | 0.392 | 0.71(0.32–1.57) | 0.403 |
| Overweight-Obesity | 16(29.10) | 1.00(0.53–1.89) | 0.990 | 1.06(0.55–2.04) | 0.868 | 1.29(0.62–2.66) | 0.495 | 1.32(0.63–2.76) | 0.456 |
| CONUT score | |||||||||
| Continuous | ... | 1.12(1.09–1.32) | <0.001* | 1.13(1.02–1.26) | 0.024* | 1.11(0.98–1.25) | 0.078* | 1.12(1.00–1.27) | 0.059* |
| Normal | 17(16.70) | Reference | Reference | Reference | Reference | ||||
| Mild risk | 54(30.50) | 2.19(1.19–4.05) | 0.012* | 1.98(1.06–3.70) | 0.033* | 1.68(0.96–3.27) | 0.082 | 1.76(0.88–3.51) | 0.089 |
| Moderate risk | 36(33.00) | 2.47(1.28–4.75) | 0.007* | 1.81(1.03–3.72) | 0.044* | 1.58(0.97–3.25) | 0.066* | 1.59(1.00–3.59) | 0.056* |
| Severe risk | 8(61.50) | 8.00(2.33–27.45) | 0.001* | 4.58(1.18–17.81) | 0.028* | 3.34(1.04–15.07) | 0.042* | 3.76(1.03–12.63) | 0.049* |
| GNRI score | |||||||||
| Continuous | ... | 0.97(0.95–0.99) | 0.004* | 0.98(0.96–1.01) | 0.133 | 0.99(0.97–1.02) | 0.721 | 0.99(0.97–1.02) | 0.618 |
| Normal | 38(22.40) | Reference | Reference | Reference | Reference | ||||
| Mild risk | 26(27.10) | 1.29(0.73–2.29) | 0.387 | 1.14(0.62–2.08) | 0.673 | 1.23(0.64–2.37) | 0.537 | 1.24(0.64–2.43) | 0.523 |
| Moderate risk | 37(35.60) | 1.92(1.12–3.29) | 0.018* | 1.42(0.78–2.55) | 0.242 | 1.20(0.62–2.34) | 0.584 | 1.30(0.66–2.55) | 0.445 |
| Severe risk | 14(45.20) | 2.86(1.29–6.33) | 0.009* | 1.71(0.70–4.15) | 0.239 | 1.21(0.45–3.26) | 0.711 | 1.22(0.45–3.35) | 0.699 |
| PNI score | |||||||||
| Continuous | ... | 0.93(0.90–0.96) | <0.001* | 0.95(0.91–0.99) | 0.008* | 0.97(0.93–1.02) | 0.213 | 0.97(0.93–1.01) | 0.133 |
| Normal | 71(24.10) | Reference | Reference | Reference | Reference | ||||
| Moderate risk | 15(31.30) | 1.43(0.73–2.78) | 0.295 | 1.17(0.57–2.39) | 0.675 | 0.99(0.44–2.23) | 0.990 | 0.97(0.42–2.24) | 0.945 |
| Severe risk | 29(49.20) | 3.04(1.71–5.40) | <0.001* | 1.93(0.98–3.79) | 0.058* | 1.33(0.61–2.92) | 0.476 | 1.43(0.64–3.19) | 0.244 |
Model 1: adjusted for age, gender, drug-resistant TB, and anemia. Model 2: adjusted for age, gender, drug-resistant TB, and anemia + diagnosis classification + BMRC stage + cerebral infarction + hydrocephalus. Model 3: adjusted for age, gender, drug-resistant TB, and anemia + diagnosis classification + BMRC stage + CSF protein + Antituberculosis therapy. BMI, body mass index; CONUT, controlling nutritional status; GNRI, geriatric nutritional risk index; PNI, prognostic nutritional index; BMRC, British Medical Research Council; CSF, cerebrospinal fluid; *p < 0.05. The bold values represented statistically significant.