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. 2025 Mar 25;167(1):90. doi: 10.1007/s00701-025-06496-6

Table 2.

α2-PI, PIC, and changes in intracranial hematoma volume

Total (n  = 30) Good outcome group (n  = 28) Poor outcome group (n  = 2) Difference (95% CI)
Hematoma volume at 1st CT scan, median (IQR), mL 9.7 (0.7–17.5) 9.7 (0.6–16.2 47.2 (1.3–93.1)  − 37.5 (− 65.1– − 2.2)
Hematoma volume at 2nd CT scan, median (IQR), mL 20.2 (5.6–48.0) 20.2 (5.3–46.9) 103.1 (12.1–194.1)  − 82.9 (− 127.7– − 24.7)
Change in hematoma volume, median (IQR), mL 10.6 (2.3–26.0) 8.9 (2.2–25.1) 55.9 (10.8–101.0)  − 47.0 (− 71.5– − 13.5)
Interval between CT scans, median (IQR), minutes 163 (133–194) 163 (128–195) 160 (136–184) 3 (− 69–80)
Plasma α2-PI activity on admission, median (IQR), % 91 (80–98) 92 (81–99) 82 (77–86) 10 (− 11–31)
Plasma PIC level on admission, median (IQR), μg/mL 5.1 (2.5–9.4) 4.9 (2.4–8.3) 27.0 (13.0–40.9)  − 22.1 (− 30.7– − 11.0)

CT Computed tomography, IQR Interquartile range, PIC Plasmin-alpha 2-plasmin inhibitor complex, α2-PI Alpha 2-plasmin inhibitor