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. 2025 Mar 11;11:e53539. doi: 10.2196/53539

Table 3.

Breast cancer trial multivariate regression analysis of predictors for health care costs.


Intervention group
(n=74)
Control group (n=75) Unstandardized coefficient SE Standardized coefficient [Exp(B)] 95% CI P value χ2/dfa
Care costs (€b)







Outpatient


All costs Mean (SD) 27,571 (6392)
n=74
26,348 (5800)
n=75
N/Ac N/A N/A N/A N/A N/A


Dependent variable: Total costs 2,040,225 1,976,097 N/A N/A N/A N/A .95d 0.042


Independent variables:









Groupe N/A N/A –0.038 0.166 0.963 0.695-1.334 .82f N/A


Age N/A N/A –0.001 0.012 0.999 0.976-1.023 .94f N/A


HRQOL N/A N/A –0.78 1.019 0.458 0.062-3.375 .44f N/A


Comorbidity N/A N/A –0.012 0.115 0.988 0.789-1.239 .92f N/A


NACTg N/A N/A 0.014 0.033 1.014 0.951-1.081 .67f N/A


Acute costs Mean (SD) 554 (597)
n=51
562 (606)
n=52
N/A N/A N/A N/A N/A N/A


Dependent variable: Acute costs 40,998 42,183 N/A N/A N/A N/A <.001d 1.170a


Independent variables:









Groupe N/A N/A 0.043 0.166 1.044 0.754-1.446 .80f N/A


Age N/A N/A –0.036 0.012 0.964 0.942-0.987 .002f N/A


HRQOL N/A N/A –4.091 1.108 0.017 0.002-0.147 <.001f N/A


Comorbidity N/A N/A 0.247 0.110 1.280 1.033-1.588 .02f N/A


NACTg N/A N/A –0.062 0.032 0.940 0.882-1.001 .05f N/A
Inpatient


All costs Mean (SD) 9206
(5254)
n=69
9093 (5460)
n=73
N/A N/A N/A N/A N/A N/A


Dependent variable: Total costs 681,221 681,949 N/A N/A N/A N/A .84d 0.341a


Independent variables:









Groupe N/A N/A 0.008 0.165 1.008 0.73-1.393 .96f N/A


Age N/A N/A –0.004 0.012 0.996 0.973-1.018 .70f N/A


HRQOL N/A N/A –1.041 1.044 0.353 0.046-2.733 .32f N/A


Comorbidity N/A N/A –0.011 0.111 0.989 0.796-1.229 .92f N/A


NACTg N/A N/A –0.01 0.033 0.990 0.928-1.056 .77f N/A

a€1=US $1.03.

bN/A: not applicable.

cP value Omnibus test General Linear Model Multivariate Regression.

dPearson χ2 value divided by degrees of freedom (goodness of fit of the model).

eIntervention/Control; Reference category=Intervention

fP value for the independent variables in the General Linear Model Multivariate Regression Model.

gNeoadjuvant chemotherapy treatments