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. 2025 Mar 25;12(1):e003091. doi: 10.1136/openhrt-2024-003091

Table 2. Type, frequency, duration, intensity, time and location of intervention of the included studies.

Study Year Type of intervention (strength, IMT, aerobic or in combination) Frequency (times per week) Duration (number of weeks) Intensity Time(length per session in minutes) Location of training
Strength training
 Scheffer et al14 2023 ST 3 12 6–8RM 45 (total) Supervised
 Shiina et al29 2019 ST+amino acid intake 3 8 15RM NR Home
 Cordina et al13 2013 ST 3 20 8RM 60 (total) Supervised
 Lahti et al34 2022 ST 3 12 4–6 RPE 30–45 (total) Supervised and home
 Avitabile et al41 2022 ST 2 24 60% MVC 60 (total) Supervised and home
IMT
 Turquetto et al27 2021 Aerobic/IMT 3 (aerobic) 7 (IMT) 16 NR (aerobic), 60% MIP (IMT) 60 (aerobic), NR (IMT) Supervised and home
 Hock et al24 2022 IMT 7 24 40% FVC 1–3 sets with 10–30 repetitions Home
 Fritz et al25 2020 IMT 7 48 Adjusted until maximum 3 sets with 10–30 repetitions Home
 Neidenbah et al30 2023 IMT 7 24 NR NR Supervised and home
 Brown et al31 2020 IMT 3 12 NR NR Home
 Laohachai et al42 2017 IMT 7 6 30% MIP 30 (total) Home
 Wu et al43 2018 IMT 5 12 40% MIP 30 (total) Supervised
Combined training
 Opotowsky et al28 2018 Aerobic+ST 2 12 NR 60 (total) Supervised and home
 Avila et al26 2016 Aerobic+ST 3 (aerobic), 2 (ST) 12 70%–80% hour 60 (total), 30–40 (ST) Supervised
 Rhodes et al11 2006 Aerobic+ST 2 12 NR (aerobic), light weight (ST) 60 (total), 20–25 (ST) Home
 Singh et al10 2007 Aerobic+ST 2 12 NR (aerobic), light weight (ST) 60 (total), 20–25 (ST) Home
 Brassard et al33 2006 Aerobic+ST 3 8 50%–80% peak V̇O2, 12–15RM (SR) 60 (total) Supervised and home
 Martinez et al35 2010 Aerobic+ST 2 12 80% hour (Aerobic), 1–2 kg (ST) 60 (total), 10 (ST) Supervised
 Gierat et al32 2015 Aerobic+ST 2–3 4 60%–80% hour, 15 RM (ST) 60 (total) Supervised
 Sutherland et al36 2018 Aerobic+ST 2 8 65%–85% hour (Aerobic), Body weight (ST) 60 (total), 20–30 (ST) Supervised and home
 Aronoff et al39 2023 Aerobic+ST 2–3 12 70%–80% hour, Light weight (ST) 60 (total), 15 (ST) Supervised and home
 Fernie et al40 2023 Aerobic+ST 3–4 48 Reserve HR 60 (total) Supervised
 Becker-Grunig et al37 2013 Aerobic+ST+IMT 7 (hospital)+5 (home) 3 (hospital)+12 (home) 60%–80% hour (aerobic)500 g–1 kg (ST), NR (IMT) 90 (hospital), 30 (home) Supervised and home
 Ferrer et al9 2020 Aerobic+ST + IMT 2 12 75% of HR (aerobic)10–15 RM (ST), 30% MIP (IMT) 70 (total)20 (ST) Supervised
 Pyykkonen et al44 2022 Aerobic+ST 2 24 NR NR Home
 Dirks et al38 2022 Aerobic+IMT 6/7 (IMT), 3 (aerobic) 40 30–50% of MIP (IMT)55% of W at V̇O2 max (aerobic) 1 set with 30 repetitions (IMT)45 min (aerobic) Home

If CON data are absent in the respective study, then not reported

FVC, forced vital capacity; HR, heart rate; IMT, inspiratory muscle training; MEP, maximal expiratory pressure; MIP, maximal inspiratory pressure; MVC, maximum voluntary contraction; NR, not reported; RM, repetition maximum; ST, strength training.