Figure 7. Effect of ADAM and MMP inhibitors on neurite outgrowth assays.

(A, B) Differentiated NG108-15 cells were treated with inhibitors as indicated (A) and the longest primary neurite from each set was measured for 45–75 neurons (B). The average neurite length in μm is plotted (y-axis). Vehicle represents the well with no MAG, D8 represents D8P1C1, D5 represents D5P2A11, and Bati represents Batimastat. For more details, see Tables S1 and S2.