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. 2025 Mar 12;15(3):404. doi: 10.3390/biom15030404
4-HNE 4-hydroxy-2-nonenal
ACTH Adrenocorticotropic hormone
AGE Advanced glycation end-product
AHR Aryl hydrocarbon receptor
AIF Apoptosis-inducing factor
AKT/PKB Protein kinase B
AMPA Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
ATP Adenosine triphosphate
BAK Bcl-2 homologous antagonist/killer
BAX Bcl-2-associated X protein
BBB Blood–brain barrier
Bcl-2 B-cell lymphoma 2
BPH Benign prostatic hyperplasia
CCL2 C-C motif chemokine ligand 2
CCL4 C-C motif chemokine ligand 4
CD25 Cluster of differentiation 25
CD4 Cluster of differentiation 4
CDK4/6 Cyclin-dependent kinases 4 and 6
CDK5 Cyclin-dependent kinase 5
CMA Chaperone-mediated autophagy
CNS Central nervous system
COPD Chronic obstructive pulmonary disease
COX-1 Cyclooxygenase 1
COX-2 Cyclooxygenase 2
CRH Corticotropin-releasing hormone
CXCL10 C-X-C motif chemokine ligand 10
CXCL12 C-X-C motif chemokine ligand 12
CXCR4 C-X-C chemokine receptor type 4
CYP3A4 Cytochrome P450 3A4
DAMPs Damage-associated molecular patterns
DC Dendritic cell
DDR DNA damage response
DHEA Dehydroepiandrosterone
DNA Deoxyribonucleic acid
DPPC Dipalmitoylphosphatidylcholine
ECM Extracellular matrix
EGFR Epidermal growth factor receptor
eNOS Endothelial nitric oxide synthase
ERK Extracellular signal-regulated kinase 1/2
FoxP3 Forkhead box P3
GDF-15 Growth differentiation factor 15
GERD Gastroesophageal reflux disease
GH Growth hormone
GHRH Growth hormone-releasing hormone
GI Gastrointestinal system
GLAST Glutamate aspartate transporter
GLT-1 Glutamate transporter 1
GM-CSF Granulocyte–macrophage colony-stimulating factor
GnRH Gonadotropin-releasing hormone
GPX7 Glutathione peroxidase 7
GSK-3β Glycogen synthase kinase 3 beta
HSP70 70 kDa heat shock protein
ICAM-1 Intercellular adhesion molecule 1
IFN-γ Interferon gamma
IGF-1 Insulin-like growth factor 1
IGFBP-2 Insulin-like growth factor binding protein 2
IKK IκB Kinase
IL-10 Interleukin 10
IL-12 Interleukin 12
IL-17 Interleukin 17
IL-18 Interleukin 18
IL-1α Interleukin 1 alpha
IL-1β Interleukin 1 beta
IL-2 Interleukin 2
IL-4 Interleukin 4
IL-6 Interleukin 6
IL-8 Interleukin 8
iNOS Inducible nitric oxide synthase
LPS Lipopolysaccharide
LTD Long-term depression
LTP Long-term potentiation
MAPK Mitogen-activated protein kinase
MDA Malondialdehyde
MEK Mitogen-activated protein kinase kinase
MMP Matrix metalloproteinase
MMP-13 Matrix metalloproteinase 13
MMP-2 Matrix metalloproteinase 2
MMP-3 Matrix metalloproteinase 3
MMP-9 Matrix metalloproteinase 9
MOMP Mitochondrial outer membrane permeabilization
NADPH Nicotinamide adenine dinucleotide phosphate (reduced form)
NFT Neurofibrillary tangle
NF-κB Nuclear factor kappa-light-chain-enhancer of activated B cells
NLRP3 NLR family pyrin domain containing 3
NMDA N-methyl-D-aspartate
NRF2 Nuclear factor erythroid 2-related factor 2
NSAID Non-steroidal anti-inflammatory drug
p16 Cyclin-dependent kinase inhibitor 2A
p21 Cyclin-dependent kinase inhibitor 1
P450 Cytochrome P450
p53 Tumor protein P53
PAR Poly (ADP-ribose)
PARP-1 Poly (ADP-ribose) polymerase 1
PEN2 Presenilin enhancer 2
PI3K Phosphoinositide 3-kinase
PPAR Peroxisome proliferator-activated receptor
PPARα Peroxisome proliferator-activated receptor alpha
PSD-95 Postsynaptic density protein 95
PTEN Phosphatase and tensin homolog
PTM Post-translational modification
PUFA Polyunsaturated fatty acid
RAAS Renin–angiotensin–aldosterone system
Rb Retinoblastoma
RNA Ribonucleic acid
RNS Reactive nitrogen species
ROS Reactive oxygen species
Runx2 Runt-related transcription factor 2
SASP Senescence-associated secretory phenotype
SCFA Short-chain fatty acid
T3 Triiodothyronine
T4 Thyroxine
TGF-β Transforming growth factor beta
TIMP Tissue inhibitor of metalloproteinase
TLR Toll-like receptor
TLR4 Toll-like receptor 4
TNFR Tumor necrosis factor receptor
TNF-α Tumor necrosis factor alpha
TP53 Tumor protein p53
Treg Regulatory T cell
UPS Ubiquitin–proteasome system
VCAM-1 Vascular cell adhesion molecule 1
VEGF Vascular endothelial growth factor
ZO Zonula occludens