CNS	Central Nervous System
LC	Liquid chromatography
DAD	Diode array detector
CV	Coefficient of variation
ACTH	Adrenocorticotropic hormone
CRH	corticotropin-releasing hormone
BD	Bipolar disorder
HPA axis	Hypothalamic–pituitary–adrenal axis
SPE	Solid phase extraction
MS	Mass spectrometry
IS	Internal standard
QC	Quality control
EMA	European Medicines Agency
LOD	Limit of detection
LLOQ	Lower limit of quantification