HNSCC	Head and neck squamous cell carcinoma
ESCRT	Endosomal sorting complex required for transport
TCGA	The Cancer Genome Atlas
VPS25	Vacuolar Protein Sorting 25 Homolog
HR	Hazard ratio
NOM	Normal oral mucosa
OS	Overall survival
DFS	Disease-free survival
TMAs	Tissue microarrays
IHC	Immunohistochemistry
TME	Tumor microenvironment
scRNA-seq	Single-cell RNA sequencing
CNV	Copy number variation
UMAP	Uniform manifold approximation and projection
pEMT	Partial epithelial–mesenchymal transition
ST	Spatial transcriptomics
DEG	Differentially expressed gene
GSEA	Gene set enrichment analysis
NES	Normalized enrichment score
FDR	False discovery rate
KEGG	Kyoto Encyclopedia of Genes and Genomes
GOBP	Gene ontology biological process
RSS	Regulon specificity score
TILs	Tumor-infiltrating lymphocytes
TIMs	Tumor-infiltrating myeloid cells
TAMs	Tumor-associated macrophages
MDSCs	Myeloid-derived suppressor cells
Tregs	Regulatory T cells
PVR	Poliovirus receptor
TIDE	Tumor immune dysfunction and exclusion
ICB	immune checkpoint blockade
Im	Immunotherapy
IC	Immunotherapy combined therapy
R	Response
NR	Non-response
CR	Complete response
PR	Partial response
SD	Stable disease
PD	Progressive disease