Items	No	Yes	Page	NA
TITLE
1. Title		X	1
ABSTRACT
2. Structured abstract		X	1
INTRODUCTION
3. Rationale		X	1
4. Objectives		X	4
METHODS
5. Eligibility criteria		X	5
6. Information sources		X	4
7. Search strategy		X	4
8. Study selection process		X	5
9. Data extraction process		X	5
10. List of data		X	5
11. Risk of bias		X	5
12. Effect measures				X
13. Synthesis methods				X
14. Assessment of publication bias				X
15. Certainty assessment				X
RESULTS
16. Study selection		X	6
17. Study characteristics		X	6
18. Risk of bias		X	14
19. Results of individual studies		X	7
20. Results of synthesis		X	10
21. Publication bias				X
22. Certainty of evidence		X
DISCUSSION
23. Discussion		X	17
OTHER INFORMATION
24. Registration and protocol		X	4
25. Funding		X	21
26. Conflict of interest		X	21
27. Availability of data				X
Note. NA: Not applicable.