| NCBI | The National Center for Biotechnology Information |
| GEO | Gene Expression Omnibus |
| TCGA | The Cancer Genome Atlas |
| DB | Disease biomarker |
| EC | Evolutionary computation |
| ML | Machine Learning |
| AD | Alzheimer’s Disease |
| PD | Parkinson’s Disease |
| TME | Tumor Microenvironment |
| scRNA-Seq | single-cell RNA sequencing |
| EBI | European Bioinformatics Institute |
| NIH | National Institutes of Health |
| CREs | Cis-Regulatory Elements |
| GA | Genetic Algorithm |
| GP | Genetic Programming |
| PSO | Particle Swarm Optimization |
| ACO | Ant Colony Optimization |
| DE | Differential Evolution |
| PDENB | Personalized Dynamic Edge-Network Biomarkers |
| MONCP | Multiobjective Optimization Network Control Principle |
| CMOP | Constrained Multi-objective Problem |
| MOP | Multi-objective optimization problem |