ICIs	Immune checkpoint inhibitors
PD-1	Programmed cell death 1
CTLA-4	Cytotoxic T lymphocyte-associated antigen-4
Trp	Tryptophan
NAD+	Nicotinamide adenine dinucleotide
IDO	Indoleamine 2,3-dioxygenase
13AA	Indole-3-acetaldehyde
HCC	Hepatocellular carcinoma
ROS	Reactive oxygen species
BH4	Tetrahydrobiopterin
IFNγ	Interferon γ
USP14	Ubiquitin-specific protease-14
Treg	Regulatory T cells
ORR	Overall response rate
MAPK	Mitogen activated protein kinases
NSCLC	Non-small cell lung cancer
TNBC	Triple negative breast cancer
VEGFR2	Vascular endothelial growth factor receptor 2
GLS	Glutaminase
TME	Tumor microenvironment
αKG	α-ketoglutarate