AAG	Albumin and alpha-1-acid glycoprotein
BALB/c	Bagg Albino
BBB	Blood–brain barrier
GLP	Good Laboratory Practice
hERG	human ether-ago-go-related gene
HPLC-ESI-MS/MS	high-performance liquid chromatography–electrospray ionization–tandem mass spectrometry
ICR	Institute of Cancer Research
PPB	Plasma protein binding
PK	Pharmacokinetic
RDT	Repeat-dose toxicology
TO	Theiler’s Original
Vd	Volume of distribution