4-(2-(Phenylamino)-6H-1,3,4-thiadiazin-5-yl)phenol—IJ28 Yellow solid; yield 60%; mp 111–112 °C; HPLC-UV: 2.85 min.; purity of 99%; 1H NMR (600 MHz, DMSO-d6) δ 3.82 (s, 2H, CH2); 6.82 (dt, 3H, J = 2.86 and 8.86 Hz, H-Ar); 7.01 (t, 1H, J = 7.46 Hz, H-Ar); 7.28 (dt, 3H, J = 1.84 and 8.01 Hz, H-Ar); 7.70 (s, 2H, H-Ar); 9.87 (s, 1H, NH); 10.12 (s, 1H, OH); 13C NMR (150 MHz, DMSO-d6) δ 159.3; 147.2; 129.1; 128.2; 126.4; 123.1; 122.0; 116.5; 115.9; 115.5; 22.6.

IJ 28