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. 2025 Feb 25;17(2):e79605. doi: 10.7759/cureus.79605

Table 4. A cross-tabulation analysis of association between ventilatory support requirements and clinical severity indicators (CAT score and modified DECAF score).

Fisher's exact test was used instead of the chi-square test due to expected cell frequencies <5 in multiple cells. *Statistically significant at p-value less than 0.05

CAT: COPD Assessment Test; DECAF: Dyspnea, Eosinopenia, Consolidation, Acidemia, and Atrial Fibrillation; IMV: Invasive mechanical ventilation; BiPAP - Bi-level positive airway pressure; NIV: Non-invasive ventilation; COPD: Chronic obstructive pulmonary disease

Ventilatory Support Requirements versus Clinical Severity Indicators Ventilation Fischer’s exact value p-value
IMV (n = 29) NIV (n = 14) BiPAP (n = 19) Room Air (n = 58)
CAT score < 10 (n = 44) 10 (22.7%) 3 (6.8%) 5 (11.4%) 26 (59.1%) 10.268 0.113
10 to 20 (n = 46) 7 (15.2%) 7 (15.2%) 10 (21.8%) 22 (47.8%)
> 20 (n = 30) 12 (40%) 4 (13.3%) 4 (13.3%) 10 (33.4%)
Modified DECAF score Low risk (n = 70) 3 (4.3%) 5 (7.1%) 8 (11.4%) 54 (77.1%) 125.237 0.001*
Intermediate risk (n = 21) 0 (0%) 8 (38.1%) 9 (42.9%) 4 (19.0%)
High risk (n = 29) 26 (89.7%) 1 (3.4%) 2 (6.9%) 0 (0%)