Fig. 1.

Laminin-dependent migration of neural progenitor cells derived from mouse E11.5 embryonic telencephalon. (A and B) Neurospheres were plated on a cover glass coated with 200 μg/ml PDL (A) or PDL plus 20 μg/ml laminin (B) and cultured for 12 h. (C) Neurospheres were cultured on a cover glass coated with 200 μg/ml PDL and the indicated different concentrations of laminin. Cell migration was assessed as described in Materials and Methods. Data are the mean ± SD of at least three independent experiments. (Bar, 250 μm.)