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ET-1 inhibits the migration of neural progenitor cells on laminin via ETB receptor. (A) Neurospheres were plated on a cover glass coated with PDL and laminin and cultured for 24 h with several concentrations of ET-1. (B) Neurospheres were treated with 10 μM BQ485, an antagonist of the ETA receptor, or 10 μM BQ788, an antagonist of the ETB receptor, for 30 min before treatment with 100 nM ET-1. Data are the mean ± SD of at least three independent experiments.
