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. 2024 Dec 28;14(2):91–96. doi: 10.1007/s13691-024-00742-x

Table 1.

Reported cases of anastrozole-induced interstitial lung disease

Authors Reported year Age (years old) Drugs Time to onset Others
Tomitaa 2010 62 Anastrozole 4 months DLST positive
55 Anastrozole 9 months DLST positive
Horiuchi [12] 2011 60 Anastrozole 12 days DLST positive
Hirohashi [11] 2015 72 Anastrozole 15 months Diedb
Fujiia 2017 56 Anastrozole 3 months DLST positive
Fujimori [10] 2019 68 Anastrozole 11 months Diedc

aThe cases were just presented in the abstract forms of the proceedings in Japanese, and the abstracts in English were not available and could not be cited in the references. The abstracts presented in Japanese were as follows: Tomita S (2010) Allergy 59(3/4): 447, Fujii K (2017) Nihon Rinsho Geka Gakkai Zassi 78:688

bThe other aromatase inhibitors (letrozole and exemestane) were administered after anastrozole withdrawal, resulting in the recurrence of interstitial lung disease after administration of each drug. She died of aspiration pneumonia

cShe died of respiratory failure (interstitial pneumonia) possibly caused by anastrozole

DLST, drug-induced lymphocyte stimulation test