Table 1.
Reported cases of anastrozole-induced interstitial lung disease
| Authors | Reported year | Age (years old) | Drugs | Time to onset | Others |
|---|---|---|---|---|---|
| Tomitaa | 2010 | 62 | Anastrozole | 4 months | DLST positive |
| 55 | Anastrozole | 9 months | DLST positive | ||
| Horiuchi [12] | 2011 | 60 | Anastrozole | 12 days | DLST positive |
| Hirohashi [11] | 2015 | 72 | Anastrozole | 15 months | Diedb |
| Fujiia | 2017 | 56 | Anastrozole | 3 months | DLST positive |
| Fujimori [10] | 2019 | 68 | Anastrozole | 11 months | Diedc |
aThe cases were just presented in the abstract forms of the proceedings in Japanese, and the abstracts in English were not available and could not be cited in the references. The abstracts presented in Japanese were as follows: Tomita S (2010) Allergy 59(3/4): 447, Fujii K (2017) Nihon Rinsho Geka Gakkai Zassi 78:688
bThe other aromatase inhibitors (letrozole and exemestane) were administered after anastrozole withdrawal, resulting in the recurrence of interstitial lung disease after administration of each drug. She died of aspiration pneumonia
cShe died of respiratory failure (interstitial pneumonia) possibly caused by anastrozole
DLST, drug-induced lymphocyte stimulation test