Table 5:

Model Classification of lung cancer risk by cancer subtype.

	NLST-test-nodules (n malignant=147, n benign=749)		Consortium-A (n malignant=238, n benign=126)
Model	SCLC (n=18)	NSCLC (n=119)	SCLC (n=39)	NSCLC (n=194)
Mayo	¶	0.810 [0.808, 0.812]	0.774 [0.772, 0.776]	0.683 [0.681, 0.685]
Brock	¶	0.792 [0.790, 0.794]	0.794 [0.792, 0.797]	0.688 [0.687, 0.690]
Liao et al.	0.683 [0.680, 0.687]	0.770 [0.768, 0.771]	0.617 [0.614, 0.620]	0.688 [0.686, 0.690]
Sybil	0.728 [0.723, 0.733] *	0.899 [0.897, 0.900] *	0.701 [0.698, 0.703]	0.701 [0.699, 0.702]
DLSTM	0.663 [0.658, 0.668]	0.808 [0.806, 0.809]	0.730 [0.726, 0.735]	0.754 [0.751, 0.757]
TDViT	0.707 [0.702, 0.711]	0.771 [0.769, 0.773]	0.667 [0.661, 0.673]	0.760 [0.757, 0.763]
DLS	0.659 [0.654, 0.664]	0.792 [0.791, 0.794]	†	†
DLI	†	†	0.904 [0.901, 0.907] *	0.853 [0.851, 0.855] *

Note.—Data are reported as bootstrapped mean area under the receiver operating characteristic curve [95% CI].

^*result was significantly different compared to each other method in the column for p<0.01

^¶prohibitive class imbalance (n=5)

^†Missing demographic, smoking history, COPD, or CYFRA covariates