Figure 3. AIMPs are associated with tumor aggressiveness, recurrence and prognosis.
AIMPs mRNA expression levels in (Ai) low (II; n=103) and high-grade (III & IV; n=218) gliomas, and (Aii) primary (n=229) and recurrent gliomas (n=62) in CGGA dataset. Student’s t-test p-value<0.05 considered statistically significant. (B) Kaplan-Meier Survival Curves depicting prognostic effects of AIMP1/2/3 mRNA expressions in CGGA, TCGA, REMBRANDT and Gravendeel cohorts of GBM. Red=high-expression green=low-expression based on median-cutoff; log-rank p-value<0.05 is considered significant.
