Figure 5. Bevacizumab treatment response is associated with specific AIMP CpG site methylation status in gliomas.

(A) Significant association between two CpG sites and astrocytoma (n=22) pathological response to bevacizumab treatment. Student’s t-test p-value<0.05 considered significant (B) Forest plots depicting Cox proportional hazards model univariate (i) and multivariate (ii) analysis for the effects of AIMP1/2/3 CpG methylation status