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. 2025 Feb 13;301(3):108308. doi: 10.1016/j.jbc.2025.108308

Figure 2.

Figure 2

Super LKB1 affects the epithelium mesenchymal transition, survival, and migration in A549-edited cells.A, Western blotting of E-cadherin, N-cadherin, and β-Actin in cWT, c2SL+, and c3SL + cells; (B) normalized levels of proteins by β-Actin (a.u); (C) scratch assay of cWT, c2SL+, and c3SL + cells treated with 60 μM of mitomycin C for 2 h; (D) quantification of scratch area after 24 h of scratch in percentage; (E) colony formation of cWT, c2SL+, and c3SL+; (F) quantification of colony number in cWT, c2SL+, and c3SL+; (G) colony area (μm) in cWT, c2SL+, and c3SL+; (H) total absorbance of violet crystal of cWT, c2SL+, and c3SL + cells colonies. Data are presented as mean ± SD. Statistical analysis was performed by ANOVA followed by Dunnet’s test ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001. These data are representative of two independent experiments.