Fig. 8.
Chronic GTS467 treatment reduced intracellular calcium levels in PFC and STR. Lesioned rats treated with saline (n = 3; i.p; 1 × /day for 3 weeks) or GTS467 (n = 4; 4mg/kg i.p; 1 × /day for 3 weeks) showed reduction in intracellular calcium levels with GTS467 treatment in (A) PFC (t7 = 2.6, **p < 0.05) and (C) STR (t7 = 2.341, P = 0.051) but had no changes in the relative expression of CAV2.2 in either PFC (B) or STR (D) determined using western blots and quantified as relative levels to the control protein β-actin. Data are represented as Mean ± S.E.M and unpaired t-test was performed to test the significance
