TABLE 1.
Demographic characteristics of the patients with bloodstream infection caused by S. maltophilia
| Demographic characteristicc | Value for indicated group
|
|||
|---|---|---|---|---|
| Total (n = 41) | Patients who died (n = 13)a | Surviving patients (n = 28) | Pb | |
| Age (mean yrs) | 50.90 | 52.08 | 50.36 | NS |
| Sex (no. of males/no. of females) | 17/24 | 7/6 | 10/18 | NS |
| No. of patients with indicated underlying illness or transplant | ||||
| Hematological malignancy | 15 | 5 | 10 | NS |
| Solid tumor | 4 | 2 | 2 | NS |
| Solid organ transplant | 1 | 0 | 1 | NS |
| Chronic renal failure | 5 | 2 | 3 | NS |
| Chronic liver disease | 1 | 0 | 1 | NS |
| Diabetes mellitus | 3 | 2 | 1 | NS |
| Duration of hospitalization before onset of bacteremia (median days) | 24 | 45 | 21 | 0.049 |
| Major surgery | 8 | 5 | 3 | 0.037 |
| Central venous catheter | 37 | 12 | 25 | NS |
| Mechanical ventilation | 11 | 8 | 3 | 0.001 |
| Previous antimicrobial therapy | 39 | 12 | 27 | NS |
| ICU stay at time of initial bacteremia | 12 | 7 | 5 | 0.018 |
| Neutropenia | 13 | 4 | 9 | NS |
| No. of patients with: | ||||
| Therapy | ||||
| Appropriate | 29 | 5 | 24 | 0.002 |
| Inappropriate | 12 | 8 | 4 | <0.001 |
| Septic shock | 7 | 7 | 0 | <0.001 |
| Indicated primary source of the bacteremia | ||||
| Pneumonia | 5 | 3 | 2 | NS |
| Central venous catheter | 9 | 2 | 7 | NS |
| Postsurgical-wound infection | 1 | 0 | 1 | NS |
| Unknown source of bacteremia | 26 | 8 | 18 | NS |
a
Thirty-day mortality.
b
NS, not significant.
c
ICU, intensive care unit. Neutropenia was defined as an absolute neutrophil count below 500 cells/mm3. Septic shock was defined as sepsis associated with evidence of organ hypoperfusion and a systolic blood pressure 90 or 30 mm Hg less than the baseline or a requirement for the use of a vasopressor to maintain blood pressure.