TABLE 2.

Comparison of AmB IRR to TNF-α and IL-1β concentrations in subjects 3 h post AmB infusion

Subject no.	Sexc	Adverse reaction(s)	TNF-α (pg/ml)		IL-1β (pg/ml)
			Baseline	3 h	Baseline	3 h
2	F	None	UDa	UD	UDb	UD
3	F	None	UD	UD	UD	UD
6	M	None	UD	UD	UD	UD
4	M	None	UD	UD	UD	1.2
9	M	None	UD	UD	UD	1.1
1	M	None	UD	52.9	UD	1.6
5	F	Chills	UD	40.6	UD	1.2
7	F	Nausea and vomiting	UD	161.1	UD	1.9
8	F	Chills	UD	26.2	2.2	3.2
11	F	Chills	UD	71.4	UD	1.2
10	M	Chills and fever	UD	53.2	UD	1.7
12	M	Chills and headache	UD	124.4	0	1.1

^aUD, undetectable TNF-α concentration (lower limit of detection, 1.6 pg/ml).

^bUD, undetectable IL-1β concentration (lower limit of detection, 0.7 pg/ml).

^cM, male; F, female.