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Inhibition of 0.1 μM [3H]hypoxanthine uptake in axenic amastigotes of L. mexicana by guanine (Gua), xanthine (Xan), and 3-deazaguanine (3-DG) (A); by 6-thioguanine (6-TG), 7-deazaguanine, and 9-deazaguanine (B); and by purine, adenine (Ade), and 1-deazapurine (1-DPur) (C). Data are expressed as percentages of control values (uptake in the absence of any inhibitor, typically 0.005 to 0.02 pmol/107 cells/s).
