TABLE 2.
Parameter | Result after administration of the following dose:
|
||
---|---|---|---|
1.3 mg/kg, i.v. | 3 mg/kg, i.v. | 6.4 mg/kg, i.p. | |
C2 min (μg/liter) | 4,417 ± 1,342 | 7,889 ± 1,367 | |
Cmax (μg/liter) | 5,390 ± 1,086 | ||
AUC0-∞ (mg · h/liter) | 1.40 ± 0.38 | 2.60 ± 0.30 | 5.0 ± 0.88 |
t1/2elim (h) | 12.1 ± 2.92 | 12.8 ± 2.51 | 13.3 ± 2.82 |
V (liters/kg) | 16.3 ± 3.85 | 15.2 ± 3.35 | 14.3 ± 2.53 |
T3 was administered by the i.v. and i.p. routes. The values are presented as means ± standard deviations.