TABLE 3.

Secondary parameters calculated by Bayesian estimation from primary parameters after TE3 administration^a

Parameter	Result after administration of the following dose:
	1.5 mg/kg, i.v.	3 mg/kg, i.v.	12 mg/kg, per os
C2 min (μg/liter)	3,310 ± 696	7,497 ± 1,248
Cmax (μg/liter)			5,916 ± 2,947
AUC0-∞ (mg · h/liter)	1.60 ± 0.27	3.35 ± 0.44	2.23 ± 0.98
t1/2elim (h)	11.2 ± 2.80	11.0 ± 2.50	12.5 ± 2.39
V (liters/kg)	12.4 ± 3.26	16.2 ± 2.70	14.2 ± 2.45

^aTE3 was administered by the i.v. and oral routes. The values are presented as means ± standard deviations.