Skip to main content
. 2005 Sep;49(9):3959–3962. doi: 10.1128/AAC.49.9.3959-3962.2005

FIG. 2.

FIG. 2.

Chlamydia culture and pulmonary histopathology findings of C. pneumoniae-infected NIH/S mice fed either a regular diet (A and C) or a high-fat diet (B and D). Mice were treated with simvastatin (0.5 mg/kg of body weight) or 1% dimethyl sulfoxide (DMSO). (A, B) Chlamydia culture results from lung tissue, median ± interquartile range (25th and 75th percentile). “a” indicates simvastatin-treated C. pneumoniae-infected regular-diet-fed mice compared to 1% DMSO-treated C. pneumoniae-infected regular-diet-fed mice; P = 0.026. (C, D) Pulmonary histopathology results, mean histology scores ± standard errors. “b” indicates simvastatin-treated C. pneumoniae-infected high-fat-diet-fed mice compared to 1% DMSO-treated C. pneumoniae-infected high-fat-diet-fed mice; P = 0.015. The nonparametric Mann-Whitney U test was used.