TABLE 1.

MICs of 11 antifungal agents against the two phases of growth of Sporothrix schenckii

Growth phase/temp (°C) (no. of isolates tested) and parameter	MIC (μg/ml)
	ABC	AMB	EBC	ITC	5FC	FLC	MFG	KTC	RVC	TRB	VRC
M/35 (34)
Range	0.125-16	1-4	0.06-4	0.25->16	16->64	>64	>128	0.03-16	1-16	0.125-4	0.5->16
GM	2.95a	1.73a	0.80	4.08a	>64	>64	>128	0.81	3.07	0.80a	9.81a
M/30 (34)
Range	0.5-16	1->16	0.06->16	0.125->16	64->64	>64	16->128	0.25-2	0.125-8	1-4	1->16
GM	7.37b	2.71b	0.96b	1.47	>64	>64	>128	0.64	2.45b	2.55b	>16b
Y/35 (24)
Range	0.06-8	1-4	<0.03-2	0.25->16	16->64	16->64	>128	0.125-4	0.25-8	0.06-1	2->16
GM	2.37	1.63	0.28c	1.06c	>64	>64	>128	0.65	5.66	0.48c	8.24c

^aStatistically significant with respect to the geometric mean MIC in the mycelial growth phase at 30°C (P < 0.05; Student's t test, paired).

^bStatistically significant with respect to the geometric mean MIC in the yeast growth phase at 35°C (P < 0.05; Student's t test, paired).

^cStatistically significant with respect to the geometric mean MIC in the mycelial growth phase at 35°C (P < 0.05; Student's t test, paired).