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. 2025 Feb 3;64(3):373–385. doi: 10.1007/s40262-025-01473-9

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© The Author(s) 2025

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Fig. 1 — Workflow for SR determination for BCS class II and IV compounds. D dose, FaSSIF fasted state simulated intestinal fluid, FaSSIF/D dose-adjusted FaSSIF solubility, SR sensitivity range