Table 1.

Selected compounds for determination of FaSSIF solubility and the conservative SR

The italics FaSSIF/D area represents the conservative SR, and the bold FaSSIF/D values represent the upper and lower limits of the conservative SR

BCS biopharmaceutical classification system, C_max maximum blood/plasma concentration, D dose, FaSSIF fasted state simulated intestinal fluid solubility, FaSSIF/D dose-adjusted FaSSIF, SR sensitivity range

^aFood effect information was provided by Boehringer Ingelheim Pharma