Table 4.
Characteristics, polysomnography (PSG), blood biochemistry, and blood cell of the severe obstructive sleep apnea (OSA) patients.
| Index | Severe OSA (n = 32) | Severe OSA with hypertension (n = 44) | P value |
|---|---|---|---|
| Characteristics | |||
| Age (year) | 40.94 ± 14.91 | 41.27 ± 11.80 | 0.700 |
| BMI (kg/m2) | 28.41 (25.95, 32.53) | 30.58 (27.90, 31.62) | 0.305 |
| Average heart rate (times/min) | 72.00 (65.00, 91.00) | 73.00 (64.50, 93.75) | 0.755 |
| Mean systolic blood pressure (mmHg) | 121.00 (111.00, 129.00) | 134.00 (126.00, 149.50) | <0.001 |
| Mean diastolic blood pressure (mmHg) | 82.00 (74.00, 87.00) | 92.00 (86.25, 99.75) | <0.001 |
| PSG | |||
| Sleep efficiency (%) | 76.20 (65.20, 82.60) | 87.00 (74.25, 88.90) | 0.015 |
| WASO (min) | 107.00 (50.90, 171.40) | 62.05 (45.93, 115.55) | 0.034 |
| Arousal index (times/hour) | 2.20 (1.40, 3.70) | 1.90 (1.03, 2.68) | 0.077 |
| N1 stage percentage (%) | 40.76 ± 27.25 | 36.96 ± 17.89 | 0.466 |
| N2 stage percentage (%) | 46.88 ± 23.74 | 43.17 ± 14.72 | 0.405 |
| N3 stage percentage (%) | 4.10 (1.00,9.30) | 3.55 (0,12.10) | 0.903 |
| AHI (times/hour) | 65.10 (51.30, 73.80) | 68.00 (57.55, 85.30) | 0.176 |
| Minimum SpO2 (%) | 71.00 (66.00, 77.00) | 67.00 (62.00, 74.00) | 0.031 |
| Oxygen desaturation index (times/hour) | 61.59 ± 19.26 | 70.80 ± 17.96 | 0.036 |
| SIT90 (%) | 0.35 (0.22, 0.46) | 0.44 (0.22, 0.58) | 0.066 |
| SIT80 (%) | 0.05 (0.02, 0.09) | 0.09 (0.03, 0.22) | 0.027 |
| Blood biochemistry | |||
| Cys-C (mg/L) | 0.89 (0.75, 1.08) | 0.96 (0.89, 1.06) | 0.312 |
| AST/ALT | 0.79 ± 0.30 | 0.69 ± 0.21 | 0.126 |
| GGT(U/L) | 42.30 (22.00, 74.00) | 48.50 (25.50, 80.50) | 0.310 |
| TG (mmol/L) | 1.71 (1.23, 2.52) | 2.00 (1.51, 2.79) | 0.312 |
| UA (mmol/L) | 435.00 ± 81.58 | 453.11 ± 102.29 | 0.410 |
| Apo-B/Apo-A | 0.95 ± 0.29 | 0.96 ± 0.26 | 0.884 |
| BUN/CREA | 0.06 (0.05, 0.08) | 0.06 (0.05, 0.07) | 0.651 |
| Blood cells | |||
| MHR | 0.34 (0.23,0.43) | 0.37 (0.27,0.55) | 0.234 |
| RBC (×1012/L) | 5.14 ± 0.40 | 5.29 ± 0.38 | 0.097 |
| HGB (g/L) | 157.00 (148.00, 163.00) | 161.50 (152.00, 166.75) | 0.106 |
| HCT (L/L) | 0.46(0.44, 0.49) | 0.47(0.45, 0.50) | 0.145 |
BMI, body mass index; WASO, wake after sleep onset; AHI, apnea-hypopnea index; SIT, supine index time; Cys-C, Cystatin-C; AST/ALT, aspartate aminotransferase/alanine aminotransferase; GGT, gamma-glutamyl transferase; TG, triglycerides; UA, uric acid; Apo-B/Apo-A, apolipoprotein B/apolipoprotein A; BUN/CREA, blood urea nitrogen/creatinine; MHR, monocyte-to-HDL cholesterol ratio; RBC, red blood cell; HGB, hemoglobin; HCT, hematocrit.