Figure 4. CUG960 +dox mice with MBNL overexpression show colocalization of epitope-tagged MBNL1 and MBNL2 with nuclear CUGexp RNA foci.
RNA FISH using a (CAG)5 locked nucleic acid probe targeting CUGexp RNA combined with IF for (A) FLAG tag and (B) MYC tag in the ventricles of CUG960 +dox mice. The experiments were conducted on 3 animals in each group, and representative images are shown. Scale bars: 10 μm.
