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. 2025 Mar 18;57(3):533–544. doi: 10.1038/s12276-025-01423-2

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© The Author(s) 2025

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Fig. 5 — a SETD6 methylation of PLK1 attenuates its protein kinase activity. b PAK4 methylation on chromatin increases its association with β-catenin, which promotes the transcription of Wnt/β-catenin target genes. The color coding is the same as in Fig. 4.