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. 2025 Mar 18;13:1552687. doi: 10.3389/fpubh.2025.1552687

Table 3.

Lung cancer hazard ratios (HRs) and 95% confidence intervals (95% CI) for men and women by categories of cumulative exposure (mg/m3-years), average exposure (mg/m3), and duration of employment (decades), all controlling for smoking; and smoking status.

Men Women
Observed HR (95% CI) Observed HR (95% CI)
Cumulative exposure
≤0.5 45 Reference 27 Reference
>0.5–1.0 25 0.8 (0.5–1.3) 22 1.0 (0.6–1.8)
>1.0–1.5 18 0.8 (0.5–1.4) 7 0.5 (0.2–1.2)
>1.5–3.0 35 0.9 (0.6–1.5) 16 0.7 (0.4–1.4)
>3–4 13 1.2 (0.7–2.3) 8 1.1 (0.5–2.6)
>4–5 10 1.2 (0.6–2.4) 4 0.8 (0.3–2.2)
>5–6 14 1.5 (0.8–2.8) 2 0.5 (0.1–2.0)
>6 34 1.0 (0.6–1.6) 4 0.6 (0.2–1.7)
Average exposure
≤0.05 85 Reference 58 Reference
>0.05–0.1 44 1.5 (1.0–2.3) 13 0.4 (0.2–0.9)
>0.1–0.15 15 1.2 (0.7–2.1) 13 0.9 (0.4–1.7)
>0.15–0.2 28 2.2 (1.4–3.6) 5 0.5 (0.2–1.3)
>0.2 22 1.3 (0.8–2.2) 1 0.4 (0.1–2.7)
Years employed
≤10 25 Reference 14 Reference
>10–20 36 0.7 (0.4–1.2) 23 0.7 (0.4–1.5)
>20–30 42 0.7 (0.4–1.1) 25 0.7 (0.4–1.3)
>30 91 0.7 (0.5–1.2) 28 0.7 (0.4–1.4)
Smoking
Never 5 Reference 16 Reference
Ever 120 17.9 (7.3–43.7) 44 6.1 (3.4–10.9)
Unknown 69 7.5 (3.0–18.6) 30 1.6 (0.9–2.9)

Age was used as the time variable. Additionally adjusted for duration of employment.