TABLE 2.
Polymyxin sensitivity of mariner mutants and wild-type meningococcal strain NMB
| Strains | MIC (μg/ml) | Insertion site |
|---|---|---|
| NMB | 512 | |
| KA2001 | 32 | mtrE |
| KA2003 | 32 | porB |
| KA2005 | 32 | mtrD |
| KA2006 | 32 | mtrD |
| KA2007 | 128 | Putative transposase |
| KA2008 | 32 | mtrC |
| KA2009 | 32 | mtrD |
| KA2010 | 32 | mtrE |
| KA2011 | 128 | NMB1060 (fbp) |
| KA2012 | 128 | NMB0596 |
| KA2013 | 64 | NMB1419 (ruvC) |
| KA2014 | 64 | fbp |
| KA2015 | 32 | NMB1559 (gshB) |
| KA2016 | 128 | fbp |
| KA2017 | 64 | NMB0205 (fur) |
| KA2018 | 32 | mtrD |
| KA2019 | 32 | mtrD |
| KA2020 | 32 | mtrD |
| KA2021 | 32 | mtrD |
| KA2022 | 32 | mtrD |
| KA2023 | 32 | mtrD |
| KA2024 | 64 | mtrD |
| KA2025 | 16 | NMB0204 |
| KA2026 | 32 | mtrD |
| KA2027 | 32 | mtrD |
| KA2028 | 32 | mtrD |
| KA2029 | 32 | mtrE |
| KA2030 | 128 | mtrR-mtrC |
| KA2031 | 32 | mtrE |
| KA2032 | 128 | mtrR-mtrC |
| XZ134 | 32 | mtrD |
| XZS3 | 8 | mtrD, NMB1052 |
| XZS8 | 8 | mtrD, NMB0355 |
| XZS9 | 8 | mtrD, NMB0355 |
| XZS17 | 8 | mtrD, NMB1150 |
| XZS18 | 2 | mtrD, lptA |
| XZS32 | 2 | mtrD, lptA |
| XZS38 | 2 | mtrD, lptA |