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. 2005 Aug;187(15):5486–5492. doi: 10.1128/JB.187.15.5486-5492.2005

TABLE 2.

S. aureus genes repressed by ArlR

N315 ORF N315 gene N315 description Change in expression level (n-fold)a agr, sar, rot, or sigB effectb
SA0104 Hypothetical protein 1.9
SA0123 Hypothetical protein 22.1 rot
SA0124 Hypothetical protein 35
SA0125 Hypothetical protein 39.6
SA0126 Hypothetical protein 20.4
SA0127 cpsM Capsular polysaccharide repeat, Unit transporter cpsM 4 rot
SA0135 Hypothetical protein 1.6
SA0136 Hypothetical protein 2.7
SA0137 Hypothetical protein 3.6
SA0138 Hypothetical protein 5.6
SA0165 Hypothetical protein 1.8 rot
SA0299 PfkB family carbohydrate kinase 2.5
SA0304 nanA N-Acetylneuraminate lyase 2.5
SA0318 Putative membrane protein 2.5
SA0319 Hypothetical protein 4.7
SA0320 Hypothetical protein 5.1
SA0321 Putative PTS multidomain regulator 5.5
SA0331 Hypothetical protein 14.2
SA0332 Hypothetical protein 8
SA0333 Conserved hypothetical protein 10.6
SA0395 Hypothetical protein 2.2
SA0710 Conserved hypothetical protein 7.4 rot
SA0850 Hypothetical protein 10.7 rot
SA0851 Oligopeptide ABC transporter, ATP-binding protein 2.2
SA0899 sspC Cysteine protease 3.1 agr +, rot
SA0904 Hypothetical protein 10.7 rot
SA0956 Hypothetical protein 2.9
SA0978 isdC Conserved hypothetical protein 1.9
SA1090 lytN LytN protein 10.4 agr +, sar +, rot −, sigB
SA1091 fmhC FmhC protein 3.9 rot
SA1145 Host factor-1 protein 3
SA1154 Conserved hypothetical protein 9.1
SA1266 Hypothetical protein 6.4
SA1267 ebhA Hypothetical protein 15.1 rot
SA1268 ebhB Hypothetical protein 28.6 agr +, rot
SA1552 Hypothetical protein 3.7
SA1577 Hypothetical protein 17.2
SA1630 splB Serine protease, V8 protease 4.3 agr +, sar +, rot −, sigB
SA1637 lukD Leukotoxin, LukD 1.9
SA1638 lukE Leukotoxin, LukE 1.6
SA1752 hlb Truncated beta-hemolysin 2.5
SA1848 nrgA Probable ammonium transporter 1.9
SA1882 kdpD Two-component sensor kinase KdpD 2.9
SA1883 kdpE Two-component response regulator KdpE 2
SA1991 lacG 6-Phospho-beta-galactosidase 4.1
SA1992 PTS system, lactose-specific IIBC component 3.5
SA1993 lacF PTS system, lactose-specific IIA component 6.5
SA1994 lacD Tagatose 1,6-diphosphate aldolase 4.4
SA1995 lacC Tagatose-6-phosphate kinase 4.9
SA1996 lacB Galactose-6-phosphate isomerase LacB subunit 7.2
SA1997 lacA Galactose-6-phosphate isomerase LacA subunit 5.1
SA2006 Hypothetical protein 5.5
SA2007 Hypothetical protein 2.8
SA2008 alsS Alpha-acetolactate synthase 2.4
SA2081 Urea transporter 3.1
SA2082 ureA Urease gamma subunit 9.3 rot
SA2083 ureB Urease beta subunit 12.1 rot
SA2084 ureC Urease alpha subunit 7 rot
SA2085 ureE Urease accessory protein UreE 5.2 rot
SA2086 ureF Urease accessory protein UreF 4.6 rot
SA2087 ureG Urease accessory protein UreG 3.6 rot
SA2088 ureD Urease accessory protein UreD 4.5 rot
SA2091 Hypothetical protein 6.7
SA2092 Hypothetical protein 4.5
SA2209 hlgC Gamma-hemolysin component C precursor 3.2 agr +, rot
SA2287 Staphylococcal regulator SarH2 7.9
SA2315 Putative membrane protein 2.6
SA2319 Putative l-serine dehydratase 3.8
SA2320 Putative membrane protein 4.7
SA2329 Murine hydrose exporter 3.8
SA2337 feoB Ferrous iron transporter protein 4
SA2338 Hypothetical protein 7.3
SA2382 Hypothetical protein 5.4
SA2455 cap8C Capsular polysaccharide synthesis enzyme Cap8C 12.7 rot −, sigB +
SA2456 cap8B Capsular polysaccharide synthesis enzyme Cap8B 18.1 rot −, sigB +
SA2457 capA Capsular polysaccharide biosynthesis CapA 31.2 rot −, sigB +
SA2482 arcA Arginine deiminase 2
SAV0397 Hypothetical protein 12.1
a

Normalized values in the arlR mutant over values in the wild-type strain.

b

agr and sar effects are as described by Dunman et al. (13), rot effect is as described by Said-Salim et al. (41), and sigB effect is as described by Bischoff et al. (4). +, up-regulated; −, down-regulated.