Table 2.

Baseline adjusted ASI-12 by intervention and usage group at 3 and 6 months

	3 Months		6 Months
	M [95%CI]	Diff. to control M [95%CI]	M [95%CI]	Diff. to control M [95%CI]
Control	51.91 [49.58, 54.24]		51.95 [49.47, 54.44]
Low usage (0–10.0)	47.49 [41.87, 53.12]	− 4.42 [− 10.55, 1.71]	48.71 [42.47, 54.94]	− 3.25 [− 9.98, 3.49]
Mid usage (10.1–20.0)	57.51 [53.99, 61.04]	5.60 [1.39, 9.81]	55.72 [51.18, 60.27]	3.77 [− 1.40, 8.94]
High usage (20.1–30.0)	60.09 [57.52, 62.67]	8.18 [4.68, 11.68]	60.82 [57.96, 63.67]	8.86 [5.04, 12.68]

Model adjusted for baseline value of the outcome, and study. p-value for group by time interaction = 0.841. There were 34, 60 and 94 participants in the low, mid and high usage groups, respectively