Schematic representation of C1-THF metabolism in mycoplasmas. FolA, dihydrofolate reductase; FolD, methylenetetrahydrofolate dehydrogenase (NADP+); Fmt, methionyl-tRNA formyltransferase; FthS, formate-dihydrofolate ligase; GlyA, glycine hydroxymethyltransferase; ThyA, thymidylate synthase; ThyX, thymidylate synthase (FAD).