TABLE 9.
Positively selected amino acid sites in inlA and actAa
| Lineage | aa residue at inlA aa site 764b
|
aa residue at actA aa site:
|
|||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 457b
|
461c
|
515b
|
522b
|
||||||||||||
| A | D | E | Kd | R | S | T | P | S | A | I | T | A | E | V | |
| I | 14e | 0 | 52e | 3 | 0 | 30 | 39e | 32 | 37 | 0 | 69e | 0 | 42e | 27e | 0 |
| II | 0 | 17e | 25 | 6 | 1 | 35e | 12 | 14 | 34 | 41e | 1 | 6e | 0 | 0 | 48e |
| III | 0 | 0 | 3 | 0 | 0 | 3 | 0 | 0 | 3 | 0 | 3 | 0 | 3 | 0 | 0 |
a
Only amino acid (aa) sites that grouped in site class with ω > 1 with posterior probabilities of >0.95 are included.
b
Sites with posterior probability of >0.95.
c
Site with a posterior probability of >0.99.
d
Only isolates that carried nonsense mutations in inlA showed K at inlA aa site 764.
e
Significant (P < 0.05) association between a specific amino acid residue and an L. monocytogenes lineage.