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. 2025 Jan 17;62(2):96–108. doi: 10.1159/000542481

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© 2025 The Author(s). Published by S. Karger AG, Basel

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Fig. 3. — a Cumulative concentration-response curve to PE in aortic rings isolated from P16 Fbn1^mgR/mgR mice (MFS; n = 12) and WT (n = 7). b KCl-induced vasoconstriction in aortic ring isolated from Fbn1^mgR/mgR mice (MFS; n = 9) and WT littermates (n = 9). c PE-induced vasoconstriction normalized over KCl maximal vasoconstriction. d Cumulative concentration-response curve to U46619, a TBXA₂ mimetic, in aortic rings isolated from Fbn1^mgR/mgR mice (MFS; n = 5) and WT littermates (n = 6). Representative α1-AR (e) and TBXA₂R (f) immunoblots of protein extracts from ascending thoracic aortas of WT and Fbn1^mgR/mgR (MFS) mice with quantitative plots shown on the bottom. No-stain labeling reagent was used as an internal control. Asterisks indicate statistical significance. TBXA₂, thromboxane A2.