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. 2025 Jan 17;62(2):96–108. doi: 10.1159/000542481

Fig. 4.

Fig. 4.

PE-dependent vasoconstriction (a) and analysis of AUC (b) in the presence or absence of the non-selective NOS inhibitor, l-NAME, in aortic ring isolated from P16 Fbn1mgR/mgR mice (MFS) and WT littermates (n = 4 per genotype and treatment). c PE-dependent vasoconstriction assessed in aortic ring isolated from P16 Fbn1mgR/mgR mice (MFS) and WT littermates before and after incubation with iNOS inhibitor, 1,400W (n = 3 per genotype and treatment). d PE-dependent vasoconstriction assessed in aortic ring isolated from P16 Fbn1mgR/mgR mice (MFS; n = 5 per treatment) and WT littermates (n = 3 per treatment) before and after incubation with SOD+catalase inhibitor. e PE-dependent vasoconstriction assessed in aortic ring isolated from P16 Fbn1mgR/mgR mice (MFS; n = 4) and WT littermates (n = 4) before and after incubation with EXP-3174, an active metabolite of AT1R inhibitor, losartan. Asterisks indicate statistical significance. SOD, superoxide dismutase; AUC, area under the curve.