Table 2.

E_max and EC₅₀ values in WT and Fbn1^mgR/mgR (MFS) mice at indicated age

Stimulus	Emax	Statistic
ACh	P16 MFS 91.6±1.49 versus P16 WT 97.9±0.52%	T test, p = 0.0016
ACh	P30 MFS 84.5±3.41 versus P30 WT 99.5±0.31%	T test, p = 0.0006
ACh	P30 MFS 84.5±3.41 versus P16 MFS 91.6±1.49%	T test, p = 0.0357
SNP	P16 MFS 99.0±1.60 versus P16 WT 100±0.00%	T test, p = 0.0762
SNP	P30 MFS 99.7±0.75 versus P30 WT 99.2±0.27%	T test, p = 0.6055
PE	P16 MFS 0.39±0.04 versus P16 WT 0.24±0.03 g/mg wet tissue	T test, p = 0.0311
PE	P30 MFS 1.1±0.07 versus P30 WT 0.8±0.04 g/mg wet tissue	T test, p = 0.0023
U46619	P16 MFS 0.77±0.23 versus P16 WT 0.73±0.24 g/mg wet tissue	T test, p = 0.8076
KCl (60 mm)	P16 MFS 0.17±0.02 versus P16 WT 0.21±0.03 g/mg wet tissue	T test, p = 0.2264
PE	P16 MFS 292.4±28.07 versus P16 WT 178.4±31.05%	T test, p = 0.0139

Stimulus	EC50	Statistic
ACh	P16 MFS −6.9±0.08 versus P16 WT −7.4±0.06 logM	T test, p < 0.0001
ACh	P30 MFS −6.7±0.21 versus P30 WT −7.6±0.27 logM	T test, p < 0.0001
ACh	P30 MFS −6.7±0.21 versus P16 MFS −6.9±0.37 logM	T test, p = 0.0954
SNP	P16 MFS −8.4±0.31 versus P16 WT −8.9±0.28 logM	T test, p = 0.0066
SNP	P30 MFS −8.2±0.14 versus P30 WT 8.4±0.11 logM	T test, p = 0.3264
PE	P16 MFS −6.7±0.37 versus P16 WT −6.5±0.26 logM	T test, p = 0.0843
U46619	P16 MFS −8.306±0.2687 versus P16 WT −8.064±0.2756 logM	T test, p = 0.1772

SNP, sodium nitroprusside.