TABLE 1.
Preferential loss of pseudogenes, intergenic DNA, and genes of unknown function in B. koehlerae and B. quintana in the chromosome II-like region (rRNA-tRNA)
| Sequence type | No. of genesa
|
|||||
|---|---|---|---|---|---|---|
| Single copy
|
Cross-hybridizing
|
|||||
| B. henselae | B. koehlerae | B. quintana | B. henselae | B. koehlerae | B. quintana | |
| Annotated | 53 | 53-53 | 48 | 7 | 4-7 | 3 |
| Conserved hypob | 25 | 23-24 | 20 | 5 | 5-5 | 3 |
| Bartonella specificc | 33 | 29-31 | 20 | 3 | 2-3 | 0 |
| r/tRNA | 0 | 0-0 | 0 | 2 | 2-2 | 4 |
| Pseudogenes | 5 | 3-3 | 3 | 6 | 1-3 | 0 |
| Intergenic DNA | 25 | 14-20 | 1 | 6 | 5 | 2 |
| Mixd | 3 | 0-1 | 0 | 3 | 2 | 0 |
| Coding DNA | 111 | 105-108 | 88 | 17 | 13-17 | 8 |
| Noncoding DNA | 33 | 17-24 | 3 | 15 | 8-10 | 2 |
| Total | 144 | 122-132 | 92 | 32 | 21-27 | 10 |
The data are shown separately for sequences represented by single-copy and cross-hybridizing sequences in the 274-kb segment flanked by an rRNA and a tRNA-Leu gene in the B. henselae genome.
The lower and upper estimates in B. koehlerae are based on M-value cutoff levels of −2 and −2.7, respectively.
The number of sequences classified as present by microarray hybridization in B. quintana is based on M-value cutoff levels of −2.
The conserved hypothetical genes have homologs in other species but their function is not known.
The Bartonella-specific genes are only present in one or more of the Bartonella species.
Mix, PCR products that cover both coding and noncoding sequences.