Table 2.
Phenotype data mapped to five categories
| Category | Discovery & Validation 1 dataset | Validation 2 dataset |
|---|---|---|
| Social impairment | SRS: Social awareness | ADI-R: Reciprocal social interaction |
| SRS: Social cognition | ADOS: Social | |
| SRS: Social communication | VINELAND: Interpersonal relationships | |
| SRS: Social motivation | VINELAND: Play and leisure time | |
| VINELAND: Coping skills | ||
| Behavior problem | BRIEF: Inhibit | ADI-R: RRBs |
| BRIEF: Shift | ADOS: Stereotyped behaviors | |
| BRIEF: Emotional control | ||
| Metacognition problem | BRIEF: Initiate | |
| BRIEF: Working memory | ||
| BRIEF: Plan/Organize | ||
| BRIEF: Organization of materials | ||
| BRIEF: Monitor | ||
| Internalizing behavior | CBCL: Anxious/Depressed | |
| CBCL: Withdrawn/Depressed | ||
| CBCL: Somatic complaints | ||
| Externalizing behavior | CBCL: Social problems | |
| CBCL: Thought problems | ||
| CBCL: Attention problems | ||
| CBCL: Rule-breaking behaviors | ||
| CBCL: Aggressive behaviors |
SRS, social response scale; BRIEF, Behavior Rating Inventory of Executive Function; CBCL, Child Behavior Checklist Ages 6–18; ADI-R, Autism Diagnostic Interview-Revised; ADOS, Autism Diagnostic Observation Schedule; VINELAND, Vineland Adaptive Behavior Scales; RRB, Restricted and repetitive behavior