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. 2025 Mar 19;16:1561199. doi: 10.3389/fphys.2025.1561199

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Copyright © 2025 Tang, Zhu, He, Wang, Chen, Li, Chen, Zhou, Wang, Liu, Yao, Liu and Zhou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of hypermobility on motor function in mice with heterotopic ossification of ligaments. (A, B) At the age of 4 weeks, exogenous stimulation was started. In the open field, mice were put to the test every 4 weeks. (C) Assessment of the effect of hypermobility on the degree of cervicothoracic ossification in mice based on the Mata scoring system, n = 6, all data are expressed as mean ± SD, # and * represent statistical differences between SH and FH groups, respectively, #p < 0.05, ##p < 0.01, ###p < 0.001, *p < 0.05, **p < 0.01, ***p < 0.001.